I love her, but I'm tired of this relationship
It is never too late to work on a relationship if you and your partner are invested in making improvements. Healthy relationships take work on the part of both parties. Congratulations on being together for eight years!! You learn a lot about yourself, your partner, and your relationship after eight years together.
Relationships can be tiring, like you mentioned, but relationships can also be rewarding. Often times there are compromises made in relationships. It sounds like sacrificing time with your family who lives up north is one of the sacrifices you have made for the sake of the relationship. Perhaps you and your partner can agree to visit your family more often, or you can visit your family alone if vacation schedules do not line up. Alternately, you can resolve this problem by having family visit you.
The comment about working too much and giving too much sound like you may not have balance in your life. Balance is a part of self-care (doing things that bring you peace). When people get closer to achieving a healthy balance in our work life or relationship, people often feel better about themselves and the relationships. It does take work and it does take practice to incorporate a daily self-care routine but the payoffs are good. Starting a self-care routine may take some trial and error at first because people often do not know what brings them peace so they will try different things until they find what works for them. It can be a time of self exploration.
I think the other question is do you want to continue the relationship. That is a question to ask yourself. Tired can mean different things to different people. If you do want to continue the relationship, try communicating your needs to your partner. Giving a lot of yourself in a relationship may feel exhausting if you are not feeling as though some of the same effort is being returned. Your partner will not know what those needs are unless you communicate them with her. When the conversation takes place, try communicating with "I" statements: I feel (insert the emotion you are feeling) when (describe the situation) because (give a reason) and what I need is (what are you wanting to happen). An example would be: I feel tired from working so hard because it does not leave me a lot of time to visit with my family up north and what I need is to find a way to maintain our lifestyle while still being able to enjoy my loved ones.