Overview

A syndrome refers to a cluster of symptoms1 that collectively indicate or characterize a disease, psychological disorder, or other abnormal condition. Unlike disorders, which are conditions that disrupt regular bodily function, syndromes involve a collection of unlinked signs, symptoms, or phenomena that occur simultaneously across different cases. There are similarities between syndromes and disorders, but they differ in that the collection of signs and symptoms that are presented by a disorder are often known to have related features or a common source, and syndromes do not. Syndromes are crucial in the field of mental health,2 where many conditions are defined by a certain set of syndromic, symptomatic behaviors.

Defining "syndrome"

Syndrome is defined as a collection of recognizable traits or abnormalities that tend to present simultaneously. The term syndrome is prevalent in mental health discussions due to the often complex and overlapping nature of mental health disorders. There are few mental health conditions classified as syndromes, identified not by a single symptom but by a particular pattern or collection of syndromic symptoms.

Despite the often-complex nature of identifying and diagnosing syndromes, understanding syndrome patterns may inform more effective mental health treatment. Early identification of syndromic patterns may enable timely intervention, preventing further progression of the syndrome and enhancing the effectiveness of syndromic treatment strategies. In the Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition (DSM-V), most mental health conditions are classified as disorders and not syndromes. 

What it is

In medical terminology, a syndrome refers to a collection of clinical signs and symptoms that co-occur and indicate a particular disease or disorder. Unlike isolated symptoms, which may arise from multiple causes, a syndrome is a specific grouping of interconnected symptoms. Syndrome symptoms often stem from the same underlying condition. A syndrome may not always point to a singular cause. Instead, syndrome describes a recognizable pattern in an individual’s condition.

Recognizing a syndrome can be beneficial because it provides a framework for healthcare professionals to understand and predict the course of a disease. This ease makes it possible to strategize an effective treatment plan for a syndrome. However, everyone's experience with a syndrome can vary. While some may experience severe syndrome symptoms, others may have milder syndrome manifestations. By understanding the syndrome as a whole, healthcare professionals can tailor syndrome treatment to the individual's unique needs, improving their mental health and overall well-being.

Syndrome vs. disorder

Syndromes and disorders, both terms in the mental health field, differ in several distinct ways. A syndrome is a cluster of symptoms that collectively indicate a certain condition, but the exact cause may not be known. For example, irritable bowel syndrome (IBS) involves a collection of symptoms like abdominal discomfort and altered bowel habits, but the cause of this syndrome is mostly unknown. IBS syndrome is classified as a syndrome due to the unclear connection between these syndromic symptoms and their cause. 

Contrarily to a syndrome, a disorder is a disruption to regular bodily or mental function with a known underlying cause. For instance, post-traumatic stress disorder (PTSD) is caused by experiencing a traumatic event and presents symptoms like flashbacks and severe anxiety. PTSD is a disorder, not a syndrome, because the origin of these symptoms are thought to stem from an initial traumatic experience.

For those experiencing trauma, support is available. Please see our Get Help Now page for more resources.

Examples

“Burnout syndrome” is a psychological term that refers to long-term exhaustion and diminished interest in work. Burnout syndrome was first coined by the American psychologist Herbert Freudenberger in the late 1970s. He used this syndrome to describe the consequences of severe stress and high ideals experienced by “helping” professions like doctors and nurses. Burnout syndrome is now commonly referred to as “compassion fatigue.” 

Burnout syndrome is characterized by a predictable, characteristic pattern of behavior that includes energy depletion, decreased accomplishment, and emotional exhaustion, etc. Burnout syndrome also includes a detachment from work-related activities and cynicism toward one's job. This syndrome involves a state of chronic3 physical and emotional exhaustion, often accompanied by cynicism and detachment. This syndrome is classified as a syndrome due to the cluster of symptoms that commonly occur for different individuals. 

Tourette's Syndrome is a physical and mental health syndrome that causes tics, which are sudden, quick movements or sounds that cannot be controlled. This syndrome's tics are distinguished as simple or complex, with the former being brief and the latter involving coordinated patterns of movements. Tourette’s syndrome is classified as a syndrome due to the combination of tics that are spoken, but may also present as physical syndromic movements.

A syndrome is a recognizable complex of symptoms and physical findings. There are only a few officially recognized mental health syndromes, with many syndromes involving a combination of physical and psychological syndromic symptoms.

Common symptoms

Mental health syndromes can exhibit a wide range of symptoms that can differ from person to person. This syndrome variation can be attributed to multiple factors, including an individual's genetic makeup, environment, and life experiences. Consequently, it may not be unusual for two individuals with the same diagnosis4 to present vastly different symptom profiles, making it challenging to establish a universal set of symptoms for any given syndrome. 

However, despite the diversity of syndromes, several common characteristics often point toward the presence of a mental health syndrome, including but not limited to the following:  

  • Consistent sadness or despair
  • Extreme mood changes
  • Difficulty concentrating or learning
  • Significant changes in eating or sleeping patterns
  • Loss of interest in hobbies and obligations

These syndrome characteristics do not necessarily constitute a diagnosis on their own but are often indicative of some level of emotional or mental distress. Recognizing these common syndrome signs may serve as the first step toward seeking professional help and treatment for a syndrome.

Associated terms

Updated on September 20, 2024.
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